Ebv and vulva carcinoma

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Aims--to detect the presence of epstein-barr virus (ebv) in cases of vulval carcinoma in chinese patients living in hong kong. Methods--formalin fixed, paraffin wax embedded blocks from eight cases of vulval carcinoma and six age matched controls of non-neoplastic vulval tissue were analysed for the presence of ebv dna using the polymerase chain reaction (pcr). To detect the presence of epstein-barr virus (ebv) in cases of vulval carcinoma in chinese patients living in hong kong. Formalin fixed, paraffin wax embedded blocks from eight cases of vulval. Lymphoepithelial carcinoma is an aggressive ebv-associated neoplasm of the nasopharyngeal region. Lymphoepithelioma-like carcinoma (lelc) of the skin, however, is a rare condition 1-4 and only three cases have been reported in the vulvar region 5-7.   aims--to detect the presence of epstein-barr virus (ebv) in cases of vulval carcinoma in chinese patients living in hong kong. Methods--formalin fixed, paraffin wax embedded blocks from eight cases of vulval carcinoma and six age matched controls of non-neoplastic vulval tissue were analysed for the presence of ebv dna using the polymerase chain reaction (pcr). Epstein-barr virus (ebv) in cases of vulval carcinoma in chinese patients livinginhongkong. Methods-formalin fixed, paraffin wax embedded blocks from eight cases of vulval carcinoma and six age matched controls of non-neoplastic vulval tissue were analysed for the presence ofebv dnausing the polymerase chain reac-tion(pcr). Aims--to detect the presence of epstein-barr virus (ebv) in cases of vulval carcinoma in chinese patients living in hong kong. Methods--formalin fixed, paraffin wax embedded blocks from eight cases of vulval carcinoma and six age matched controls of non-neoplastic vulval tissue were analysed for the presence of ebv dna using the polymerase chain reaction (pcr).   lymphoepithelial carcinoma is an aggressive ebv-associated neoplasm of the nasopharyngeal region. Lymphoepithelioma-like carcinoma (lelc) of the skin, however, is a rare condition 14 and only three cases have been reported in the vulvar region 57. This report describes an unusual ebv-negative lymphoepithelioma-like carcinoma of the vulva in a 73-year-old patient. The lesion was localised at the right minor labium and was resected by partial vulvectomy. A synchronous sentinel lymph node biopsy revealed a single micrometastasis in the right inguinal region, which prompted local radiotherapy.   oncoviruses such as hpv, kshv, and ebv have been reported in patients with hiv infection and aids. How oncovirus-associated cancers rise in aids patients has not been fully established. The purpose of our study was to identify the viral agents in vulvar cancer and to assess their contribution to pathogenesis. We retrospectively identified a total of 13 vulva tissue samples from hiv-1 positive. Low copy number of ebv dna was found in 9 cases of lelc (1-14. 8-1586 copiesmicrog) using real-time quantitative pcr bam h1 w fragment probe, but ebv-encoded rna-in situ hybridization was negative in tumor cells.

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